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Lab test

Tetanus Antitoxoid Test

The tetanus antitoxoid test measures the level of antibodies against tetanus in a blood sample. Quest describes it as a way to evaluate antibody response following immunization with Tetanus Antitoxoid.

Blood drawQuest patient service center

About this test

Tetanus antitoxoid antibody reflects the immune system's response to tetanus vaccination. Quest lists this test under names including Tetanus Toxin Antibody and Tetanus Toxoid Antibody, and it is analyzed using an immunoassay method on a serum sample.

Quest notes that tetanus, caused by the bacterium Clostridium tetani, can still occur in some individuals even when their antibody levels would otherwise be considered protective, and that results should not be used to determine whether antitoxin administration is clinically necessary. Because of that, a clinician reads the result in the context of the person's vaccination history and clinical situation rather than as a stand-alone answer.

Test details

Quest code4862
MethodologyImmunoassay
Sample type1 mL serum
CollectionQuest patient service center

Reference range

≥0.10 IU/mL

Reference ranges are general guidance. The range printed on your own laboratory report is the one that applies to your result.

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Quest resources

Additional details

What this test looks at

The test reports the level of tetanus antitoxoid antibody in a serum sample, measured by immunoassay. Quest lists it under several names, including Tetanus Toxin Antibody and Tetanus Toxoid Antibody, that all refer to this same measurement.

Order online and a physician order is included — no doctor's visit and no insurance needed. Your sample is collected at a Quest Diagnostics patient service center.

Laboratory results should always be interpreted by a licensed clinician who knows your health history. This page is information about a test, not medical advice.

Frequently asked questions

What does the tetanus antitoxoid test measure?

It measures the level of antibodies against tetanus in a serum sample, using an immunoassay method. Quest describes this as a way to evaluate the antibody response following Tetanus Antitoxoid immunization.

How is the sample collected?

The test uses a 1 mL serum sample from a routine blood draw at a Quest Diagnostics patient service center.

Do I need to prepare for this test?

No preparation instructions are listed for this test, though people follow any instructions their ordering clinician provides.

Does a protective antibody level mean tetanus can't happen?

No. Quest notes that tetanus, caused by Clostridium tetani, can still occur in some individuals even with antibody levels that would otherwise be considered protective.

Can this result tell a clinician whether antitoxin treatment is needed?

No. Quest states that results should not be used to determine whether antitoxin administration is clinically necessary; that decision is made by the clinician based on the broader clinical picture.

How much is a Tetanus Antitoxoid test?

$59, paid once at checkout. The price includes the physician's order this test requires and sample collection at a Quest patient service center.

Last updated 2026-09-18 · How we write about lab testing

Educational content

This page is for general educational purposes only. It is not medical advice, and it is not a substitute for consultation with a qualified healthcare professional. Laboratory results should always be interpreted by a licensed clinician who knows your health history. If you have questions about your health or your results, talk with your doctor. If you think you may be experiencing a medical emergency, call 911.