Sjögren's Antibody (SS-B) Test
The Sjögren's Antibody (SS-B) test measures SS-B antibody in a blood sample. Quest describes SS-B as present in about 15% of people with Sjögren's Syndrome, and notes it is not found without SS-A antibody also being present.
About this test
SS-B is one of two antibodies associated with Sjögren's Syndrome. Quest reports that SS-B is detected in roughly 15% of people with the condition, and that it only appears when SS-A antibody is also present, which is why the two are often ordered together.
Who might consider this test?
- People who consider this test are usually being evaluated for Sjögren's Syndrome, often alongside the SS-A antibody test.
Test details
| Quest code | 38569 |
|---|---|
| Methodology | Immunoassay |
| Sample type | 1 mL serum |
| Collection | Quest patient service center |
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Quest resources
Additional details
How it's often used alongside other tests
SS-B is described as appearing only when SS-A antibody is also present, so this test is often ordered together with the SS-A antibody test. Quest notes that finding both antibodies together strengthens the diagnosis of Sjögren's Syndrome and conveys prognostic information compared with either alone. This test is also listed under the alias Sjogrens.
Order online and a physician order is included — no doctor's visit and no insurance needed. Your sample is collected at a Quest Diagnostics patient service center.
Laboratory results should always be interpreted by a licensed clinician who knows your health history. This page is information about a test, not medical advice.
Frequently asked questions
What does the SS-B antibody test measure?
It measures the presence of Sjögren's Antibody (SS-B) in a serum sample, using immunoassay methodology.
How is the sample collected?
The test uses a 1 mL serum sample from a routine blood draw.
Do I need to prepare for this test?
No preparation instructions are listed for this test, though people follow any instructions their ordering clinician provides.
Is SS-B tested together with SS-A?
It is. Quest notes that SS-B antibody only appears when SS-A is also present, and that finding both together strengthens a Sjögren's Syndrome diagnosis and adds prognostic information.
How common is a positive SS-B result in Sjögren's Syndrome?
Quest reports that SS-B antibody is detected in about 15% of people with Sjögren's Syndrome, always alongside SS-A.
How much does the Sjogren's Antibody test cost?
The cash price at Celio Health is $200. That covers the physician's order and sample collection at a Quest patient service center — no insurance is needed and there's no separate doctor's visit to pay for.