Sjögren's Antibody (SS-A) Test
The Sjögren's Antibody (SS-A) test measures SS-A antibody in a blood sample. Quest describes SS-A as one of two antibodies associated with Sjögren's Syndrome, the other being SS-B, and notes that finding both together strengthens the diagnosis and adds prognostic information.
About this test
SS-A is an antibody clinicians look at when evaluating Sjögren's Syndrome, an autoimmune condition. Quest's description pairs it with a second antibody, SS-B: when both are detected together, that combination is described as strengthening the diagnosis and providing prognostic information, compared with either antibody alone.
Quest also notes that SS-B antibody is reported as present only when SS-A is also detected, which is part of why the two antibodies are often considered together rather than SS-A being read in isolation.
Test details
| Quest code | 38568 |
|---|---|
| Methodology | Immunoassay |
| Sample type | 1 mL serum |
| Collection | Quest patient service center |
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Quest resources
Additional details
How it's often used alongside other tests
Quest ties the clinical usefulness of SS-A to also having an SS-B result: together they can strengthen a Sjögren's Syndrome diagnosis and add prognostic information, while SS-B alone is not reported as present without SS-A. This test is also listed under the alias Sjogrens.
Order online and a physician order is included — no doctor's visit and no insurance needed. Your sample is collected at a Quest Diagnostics patient service center.
Laboratory results should always be interpreted by a licensed clinician who knows your health history. This page is information about a test, not medical advice.
Frequently asked questions
What does the SS-A antibody test measure?
It measures the presence of Sjögren's Antibody (SS-A) in a serum sample, using immunoassay methodology.
How is the sample collected?
The test uses a 1 mL serum sample from a routine blood draw.
Do I need to prepare for this test?
No preparation instructions are listed for this test, though people follow any instructions their ordering clinician provides.
Is SS-A tested together with SS-B?
It is often considered alongside SS-B. Quest notes that SS-B antibody is only reported as present when SS-A is also detected, and that finding both together strengthens a Sjögren's Syndrome diagnosis and adds prognostic information.
What does a positive SS-A result mean on its own?
Quest describes SS-A as one of two antibodies associated with Sjögren's Syndrome; a clinician reads it together with the SS-B result and a person's symptoms and history.
Can I get the Sjogren's Antibody test without a doctor's visit or insurance?
Yes. The $200 cash price includes an independent physician's order, so no referral is needed, and insurance is never involved.