Scleroderma Antibody (Scl-70) Test
The Scleroderma Antibody (Scl-70) test measures Scl-70 antibody in a blood sample. Quest describes this antibody as present in roughly 40% of people with progressive systemic sclerosis, and it is read as one part of a broader evaluation rather than on its own.
About this test
Scl-70 antibody is one of several antibodies clinicians look at when evaluating connective tissue conditions. Quest reports that it is found in about 40% of people with progressive systemic sclerosis (PSS), which is why its presence is associated with evaluation for that condition.
Who might consider this test?
- Present in only a portion of people with progressive systemic sclerosis
- A negative result does not rule out the condition
Test details
| Quest code | 4942 |
|---|---|
| Methodology | Immunoassay |
| Sample type | 1 mL serum |
| Collection | Quest patient service center |
Reference range
<1.0 AI Negative
Reference ranges are general guidance. The range printed on your own laboratory report is the one that applies to your result.
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Quest resources
Additional details
What this test looks at
The test reports a single result: the presence of Scl-70 antibody in serum, measured by immunoassay. Quest lists this analyte as SCL-70 ANTIBODY, and no other analytes are reported with this test.
Order online and a physician order is included — no doctor's visit and no insurance needed. Your sample is collected at a Quest Diagnostics patient service center.
Laboratory results should always be interpreted by a licensed clinician who knows your health history. This page is information about a test, not medical advice.
Frequently asked questions
What does the Scl-70 antibody test measure?
It measures the presence of Scl-70 antibody in a serum sample, using immunoassay methodology.
How is the sample collected?
The test uses a 1 mL serum sample from a routine blood draw.
Do I need to prepare for this test?
No preparation instructions are listed for this test, though people follow any instructions their ordering clinician provides.
What does a Scl-70 antibody result relate to?
Quest reports that Scl-70 antibody is found in about 40% of people with progressive systemic sclerosis (PSS), so its presence is associated with evaluation for that condition.
How much is a Scleroderma Antibody test?
$200, paid once at checkout. The price includes the physician's order this test requires and sample collection at a Quest patient service center.