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Lab test

Quantitative Thyroglobulin (without Thyroglobulin Antibodies) Test

This test measures thyroglobulin (TG) in a serum sample. Quest describes it as used mainly to monitor, not diagnose, people with well-differentiated thyroid cancer, and it can be ordered through Celio Health.

Blood drawQuest patient service center

About this test

Thyroglobulin is produced only by the thyroid gland, so its concentration in blood reflects thyroid tissue activity or presence. A 1 mL serum sample is analyzed using immunoassay methods that measure the amount of thyroglobulin present. Quest also lists this test under the alias Thyroglobulin.

Quest describes the main use of this test as monitoring, not diagnosing, people with well-differentiated thyroid cancer: after thyroid removal and ablation, it may help determine whether metastasis is present. Quest also notes that deficient TG synthesis has been observed in infants with goitrous hypothyroidism.

Test details

Quest code15561
MethodologyImmunoassay
Sample type1 mL serum
CollectionQuest patient service center

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Quest resources

Additional details

What this test looks at

The test reports one value: thyroglobulin concentration in serum. Because thyroglobulin is made only by the thyroid gland, Quest describes it as reflecting thyroid tissue activity, which is why it is used to monitor people after thyroid removal and ablation for well-differentiated thyroid cancer, to help determine whether metastasis is present.

Order online and a physician order is included — no doctor's visit and no insurance needed. Your sample is collected at a Quest Diagnostics patient service center.

Laboratory results should always be interpreted by a licensed clinician who knows your health history. This page is information about a test, not medical advice.

Frequently asked questions

What does this test measure?

It measures the level of thyroglobulin (TG) in a serum sample, using immunoassay methods.

How is the sample collected?

The test uses a 1 mL serum sample from a routine blood draw.

Do I need to prepare for this test?

No preparation instructions are listed for this test, though people follow any instructions their ordering clinician provides.

Is this test used to diagnose thyroid cancer?

Quest describes it as used to monitor, not diagnose, people with well-differentiated thyroid cancer, so it is used for monitoring or screening, not diagnosis on its own.

Why doesn't this version include thyroglobulin antibodies?

Quest notes that in immunometric assays, thyroglobulin antibodies can interfere and produce inappropriately low thyroglobulin results, which is why this test is reported without that antibody measurement.

How much is a Thyroglobulin Quantitative without Thyroglobulin Antibodies test?

$75, paid once at checkout. The price includes the physician's order this test requires and sample collection at a Quest patient service center.

Last updated 2026-09-18 · How we write about lab testing

Educational content

This page is for general educational purposes only. It is not medical advice, and it is not a substitute for consultation with a qualified healthcare professional. Laboratory results should always be interpreted by a licensed clinician who knows your health history. Laboratory tests of this kind are used for screening and monitoring, not for diagnosis on their own — a diagnosis can only be made by a licensed clinician who evaluates results in the context of your health history and examination. If you have questions about your health or your results, talk with your doctor. If you think you may be experiencing a medical emergency, call 911.