RPR (Monitor) with Reflex to Titer (REFL)
This RPR test is used to monitor people already diagnosed with syphilis rather than to make an initial diagnosis. It measures nontreponemal antibody reactivity in serum, and a reactive result is reflexed to a titer.
About this test
This RPR test is used to monitor people who have already been diagnosed with syphilis, rather than to make an initial diagnosis. It measures nontreponemal (lipoidal antigen) antibody reactivity in a 1 mL serum sample using flocculation methodology; a reactive result is reflexed to a titer.
Quest notes that the titer may correlate with disease activity and typically decreases with treatment. Follow-up testing is recommended using the same nontreponemal test and the same laboratory so results stay comparable over time.
Test details
| Quest code | 92156 |
|---|---|
| Methodology | Flocculation |
| Sample type | 1 mL serum |
| Collection | Quest patient service center |
Reference range
Non-Reactive
Reference ranges are general guidance. The range printed on your own laboratory report is the one that applies to your result.
Related tests and panels
Measures nontreponemal antibodies related to syphilis, used to monitor patients p…
Quest resources
Additional details
What this test looks at
The test reports nontreponemal antibody reactivity, and a reactive result is automatically reflexed to a titer measurement. Quest notes that true positive results with this kind of test can also occur with autoimmune disease, cancer, other infections, older age and pregnancy, which is part of why the result is read in the context of a person's history rather than alone.
This test isn't orderable through the store yet. Requesting it tells us you want it and puts you on the list to be told when that changes — there is no charge and no commitment, and requesting does not place an order.
Laboratory results should always be interpreted by a licensed clinician who knows your health history. This page is information about a test, not medical advice.
Frequently asked questions
What does this test measure?
Nontreponemal antibody reactivity in serum, using flocculation methodology; a reactive result is reflexed to a titer measurement.
How is the sample collected?
The test uses a 1 mL serum sample from a routine blood draw.
Do I need to prepare for this test?
No preparation instructions are listed for this test, though people follow any instructions their ordering clinician provides.
Who is this monitoring test for?
Quest describes it as used to monitor people previously diagnosed with syphilis, with follow-up recommended at six to twelve months for primary and secondary syphilis.
Why does Quest recommend using the same lab each time?
Because the titer is compared against earlier results over time, using the same nontreponemal test and laboratory keeps results comparable.