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Lab test

ACTH Plasma Test

This test measures levels of adrenocorticotropic hormone to evaluate adrenal and pituitary function and helps evaluate hormone imbalances like Addison's disease or Cushing's syndrome.

Blood drawQuest Diagnostics

About this test

Measures adrenocorticotropic hormone (ACTH) in plasma, a pituitary hormone that stimulates cortisol production by the adrenal glands.

Plasma concentration of ACTH, a 39-amino-acid peptide hormone produced by the pituitary gland that stimulates the adrenal cortex to form and secrete glucocorticoids such as cortisol.

Test details

Quest code211
MethodologyElectrochemiluminescence
Sample type1.5 mL frozen plasma collected in an EDTA (lavender-top) tube
Patient preparationACTH measurement is not recommended for patients who have been administered cosyntropin (ACTH(1-24)) because the results may be falsely elevated or depressed
CollectionQuest patient service center

Reference range

7.2-63.3 pg/mL

Reference ranges are general guidance. The range printed on your own laboratory report is the one that applies to your result.

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Quest resources

Additional details

A physician order is included — no doctor's visit and no insurance needed. Your sample is collected at a Quest Diagnostics patient service center.

Results will be emailed securely and will also be available in your Celio account. Laboratory results should always be interpreted by a licensed clinician who knows your health history. This page is information about a test, not medical advice.

Frequently asked questions

How much does the ACTH Plasma Test cost?

$149. That is the full cash-pay price for this test and it includes the physician order. No insurance is billed and there are no memberships or subscriptions.

Do I need a doctor's visit or insurance?

No. Celio Health arranges the physician's order for the tests you select, so you can order online without a separate doctor visit and without billing insurance.

Where do I get my sample collected?

At a Quest Diagnostics patient service center. After ordering you receive your requisition and choose a location that suits you.

How long do results take?

Most results are available with timing that varies by test and collection location after your sample is collected, delivered securely to your Celio Health account.

Do I need to prepare for this test?

ACTH measurement is not recommended for patients who have been administered cosyntropin (ACTH(1-24)) because the results may be falsely elevated or depressed. This is the preparation Quest publishes for this test; if your clinician gives you different instructions, follow theirs.

Last updated 2026-09-14 · How we write about lab testing

Educational content

This page is for general educational purposes only. It is not medical advice, and it is not a substitute for consultation with a qualified healthcare professional. Laboratory results should always be interpreted by a licensed clinician who knows your health history. Laboratory tests of this kind are used for screening and monitoring, not for diagnosis on their own — a diagnosis can only be made by a licensed clinician who evaluates results in the context of your health history and examination. If you have questions about your health or your results, talk with your doctor. If you think you may be experiencing a medical emergency, call 911.