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Lab test

Crystals, Synovial Fluid Test

The synovial fluid crystals test examines a sample of joint fluid under polarized light microscopy to check for pathologic crystals. Quest also lists it as the Uric Acid Crystals test.

Quest patient service center

About this test

This test looks for the presence of pathologic crystals in a sample of synovial (joint) fluid. Quest analyzes the 3 mL sample, collected in an EDTA or sodium heparin tube, using microscopy under polarized light, a method that allows different crystal types to be distinguished by how they interact with polarized light.

Quest describes this test as used to rule out pathologic crystals in synovial fluid. The site the fluid was drawn from is recorded alongside the crystal finding as part of the report.

Test details

Quest code4563
MethodologyMicroscopy/Polarized Light
Sample type3 mL synovial fluid
CollectionQuest patient service center

Reference range

None seen

Reference ranges are general guidance. The range printed on your own laboratory report is the one that applies to your result.

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Quest resources

Additional details

What this test looks at

The test examines synovial fluid under polarized light microscopy to check for the presence of pathologic crystals, along with recording the joint site the sample came from. Quest lists this product under names including Crystals, Synovial Fluid and Uric Acid Crystals.

Order online and a physician order is included — no doctor's visit and no insurance needed. Your sample is collected at a Quest Diagnostics patient service center.

Laboratory results should always be interpreted by a licensed clinician who knows your health history. This page is information about a test, not medical advice.

Frequently asked questions

What does this test look for?

It looks for the presence of pathologic crystals in a sample of synovial (joint) fluid, examined under polarized light microscopy.

How is the sample collected?

The test uses a 3 mL sample of synovial fluid, collected in an EDTA or sodium heparin tube, obtained by a clinician from the joint being evaluated.

Do I need to prepare for this test?

No preparation instructions are listed for this test, though people follow any instructions their ordering clinician provides.

Why might this test be ordered?

Quest describes this test as used to rule out pathologic crystals in synovial fluid.

What does a Crystals, Synovial Fluid test cost without insurance?

$249. Celio Health's price is a flat cash price and insurance is never billed: the required physician's order is included.

Last updated 2026-09-18 · How we write about lab testing

Educational content

This page is for general educational purposes only. It is not medical advice, and it is not a substitute for consultation with a qualified healthcare professional. Laboratory results should always be interpreted by a licensed clinician who knows your health history. If you have questions about your health or your results, talk with your doctor. If you think you may be experiencing a medical emergency, call 911.