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Lab test

Collagen Type I C-Telopeptide (CTx) Test

The CTx test measures Collagen Type I C-Telopeptide in a blood serum sample. Quest describes this substance as associated with bone resorption, the breakdown of bone tissue.

Quest patient service center

About this test

CTx is measured in serum using an immunoassay method. Quest describes it as a marker that may be used to assess bone resorption in metabolic bone disease, and to monitor therapy intended to slow or halt bone loss associated with osteoporosis.

Quest lists specific preparation for this test: fasting for a minimum of 12 hours, and, for people taking biotin supplements, timing the blood draw relative to the last dose, since biotin can affect certain lab methods. These instructions appear with the test details, and following them helps the result reflect a person's baseline level accurately.

Who might consider this test?

  • Typically working with a clinician on metabolic bone disease or osteoporosis
  • The marker is used to track bone resorption over time
  • Including in response to therapy aimed at slowing bone loss

Test details

CollectionQuest patient service center

Quest resources

Additional details

What this test looks at

The test reports a single value: the level of C Telopeptide (CTx) in a 1 mL serum sample, measured by immunoassay.

This test isn't part of the Celio Health store at the moment, so it can't be ordered or requested here. The test menu lists everything that can.

Laboratory results should always be interpreted by a licensed clinician who knows your health history. This page is information about a test, not medical advice.

Frequently asked questions

What does the CTx test measure?

It measures Collagen Type I C-Telopeptide in a serum sample, using an immunoassay method. Quest associates this marker with bone resorption, the breakdown of bone tissue.

How is the sample collected?

The test uses a 1 mL serum sample from a routine blood draw.

Do I need to prepare for this test?

Yes. Quest lists preparation for this test: fasting for a minimum of 12 hours, and, for people on biotin supplements, having blood drawn a set number of hours after the last dose. These details appear with the test.

How might this test be used?

Quest describes it as used to assess bone resorption in metabolic bone disease and to monitor therapy aimed at slowing or halting bone loss associated with osteoporosis.

Last updated 2026-09-18 · How we write about lab testing

Educational content

This page is for general educational purposes only. It is not medical advice, and it is not a substitute for consultation with a qualified healthcare professional. Laboratory results should always be interpreted by a licensed clinician who knows your health history. If you have questions about your health or your results, talk with your doctor. If you think you may be experiencing a medical emergency, call 911.