Cell Count and Differential, Synovial Fluid Test
This test examines a synovial (joint) fluid sample for its cell population, reporting cell counts and the differential breakdown of cell types present. Quest describes these measurements as reflecting changes associated with various disorders affecting the joint.
About this test
The panel reports appearance, color, site, total nucleated cell count and the percentage breakdown of cell types in synovial fluid, including neutrophils, lymphocytes, monocytes/macrophages, eosinophils, basophils and synoviocytes. Quest analyzes a 3 mL sample, collected in an EDTA or sodium heparin tube, using an automated analyzer and/or manual microscopic examination.
Quest notes that immunologic, mechanical, chemical or bacteriologic damage to joint membranes and capillaries may be associated with varying degrees of inflammatory response, which can change the cell population and chemical makeup of joint fluid. Because the panel reports several values together, a clinician reads the full set in the context of the joint being evaluated.
Test details
| Quest code | 4562 |
|---|---|
| Methodology | Automated analyzer and/or Manual Microscopic examination |
| Sample type | 3 mL synovial fluid |
| Collection | Quest patient service center |
Related tests and panels
Measures arsenic in whole blood, used in monitoring arsenic exposure and certain…
Measures chromium in a urine sample, related to occupational, environmental or…
Measures seven heavy metals in urine, a panel used to assess exposure to…
Quest resources
Additional details
What this test looks at
The panel reports total nucleated cell count along with the percentage of neutrophils, lymphocytes, monocytes/macrophages, eosinophils, basophils and synoviocytes, plus the fluid's appearance and color. These values describe the cell population of the joint fluid sample submitted.
Order online and a physician order is included — no doctor's visit and no insurance needed. Your sample is collected at a Quest Diagnostics patient service center.
Laboratory results should always be interpreted by a licensed clinician who knows your health history. This page is information about a test, not medical advice.
Frequently asked questions
What does this test measure?
It measures the total nucleated cell count and the percentage breakdown of cell types in synovial (joint) fluid, along with the fluid's appearance and color.
How is the sample collected?
The test uses a 3 mL synovial fluid sample, collected in an EDTA (lavender-top) or sodium heparin (green-top) tube.
Do I need to prepare for this test?
No preparation instructions are listed for this test, though people follow any instructions their ordering clinician provides.
Why might a clinician order this test?
Quest notes that immunologic, mechanical, chemical or bacteriologic damage to joint membranes and capillaries may be associated with varying degrees of inflammatory response, which can change the cell population and chemical makeup of joint fluid.
How much is a Cell Count and Differential, Synovial Fluid test?
$95, paid once at checkout. The price includes the physician's order this test requires and sample collection at a Quest patient service center.