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Lab test

Hepatitis B Surface Antibody Immunity, Quantitative Test

This test measures the concentration of antibodies against the Hepatitis B virus surface antigen, reported as a quantitative value. Quest describes it as used to assess immune status following vaccination or infection, based on CDC guidelines.

Blood drawQuest patient service center

About this test

Hepatitis B surface antibody develops after a successful immune response to Hepatitis B vaccination, or after recovering from infection. This quantitative version reports the antibody amount as a value rather than only a positive or negative result, which Quest describes as used to determine immune status per CDC guidelines.

The test uses a 1 mL serum sample, analyzed by immunoassay. Quest lists it under the name Hepatitis B Surface Antibody Immunity, Quantitative, reflecting that it is a numeric measure of antibody level rather than a simple detected/not detected result.

Who might consider this test?

  • Because the result is a quantitative value, a clinician reads it against CDC guidance for what counts as an immune level.

Test details

Quest code8475
MethodologyImmunoassay
Sample type1 mL serum
CollectionQuest patient service center

Reference range

≥10 mIU/mL

Reference ranges are general guidance. The range printed on your own laboratory report is the one that applies to your result.

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Quest resources

Additional details

What this test looks at

The test reports the quantitative concentration of Hepatitis B surface antibody in a serum sample, analyzed by immunoassay. Quest describes the result as used to assess immune status following vaccination or infection, based on CDC guidelines, rather than simply reporting whether antibody is present.

Order online and a physician order is included — no doctor's visit and no insurance needed. Your sample is collected at a Quest Diagnostics patient service center.

Laboratory results should always be interpreted by a licensed clinician who knows your health history. This page is information about a test, not medical advice.

Frequently asked questions

What does this test measure?

It measures the concentration of Hepatitis B surface antibody in a serum sample, reported as a quantitative value.

How is the sample collected?

Through a routine blood draw, collected as a 1 mL serum sample.

Do I need to prepare for this test?

No preparation instructions are listed for this test, though people follow any instructions their ordering clinician provides.

What is this test used to assess?

Quest describes it as used to assess immune status against Hepatitis B, following vaccination or infection, based on CDC guidelines.

How is this different from a qualitative Hepatitis B surface antibody test?

This version reports a quantitative antibody value rather than only a positive or negative result.

How much is a Hep B Surface Antibody Immunity, Quant test?

$149, paid once at checkout. The price includes the physician's order this test requires and sample collection at a Quest patient service center.

Last updated 2026-09-18 · How we write about lab testing

Educational content

This page is for general educational purposes only. It is not medical advice, and it is not a substitute for consultation with a qualified healthcare professional. Laboratory results should always be interpreted by a licensed clinician who knows your health history. If you have questions about your health or your results, talk with your doctor. If you think you may be experiencing a medical emergency, call 911.