Epstein-Barr Virus Viral Capsid Antigen (VCA) Antibody, IgM Test
This test measures IgM antibody to the Epstein-Barr virus viral capsid antigen (VCA) in a serum sample. Because this antibody is transient, its presence is associated with a recent or current EBV infection rather than one from the past.
About this test
VCA IgM is one of several antibodies the body makes in response to Epstein-Barr virus (EBV). Quest also lists this test as EBV Current Infection, VCA IgM, EBV Capsid Antibody IgM, and EBV VCA IgM. It is measured by immunoassay from a 1 mL serum sample.
This antibody is typically detectable at the time of clinical presentation, then declines to undetectable levels within about a month in young children and within about three months in others. EBV infection is associated with infectious mononucleosis, usually a self-limiting illness in children and young adults, and has also been linked to lymphoproliferative disorders, including tumors.
Test details
| Quest code | 8426 |
|---|---|
| Methodology | Immunoassay |
| Sample type | 1 mL serum |
| Collection | Quest patient service center |
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Quest resources
Additional details
What this test looks at
The test reports one value: the level of IgM antibody to EBV's viral capsid antigen in serum. It is detectable early in the course of infection and then declines, so a positive result points toward a recent or current infection rather than one from further in the past. A clinician reads it alongside the other EBV antibodies and a person's symptoms and history.
Order online and a physician order is included — no doctor's visit and no insurance needed. Your sample is collected at a Quest Diagnostics patient service center.
Laboratory results should always be interpreted by a licensed clinician who knows your health history. This page is information about a test, not medical advice.
Frequently asked questions
What does this test measure?
It measures the level of IgM antibody to the Epstein-Barr virus viral capsid antigen (VCA) in a serum sample, using immunoassay methodology.
How is the sample collected?
The test uses a serum sample from a routine blood draw at a Quest Diagnostics patient service center.
Do I need to prepare for this test?
No preparation instructions are listed for this test, though people follow any instructions their ordering clinician provides.
How long does this antibody stay detectable?
It is typically detectable at the time of clinical presentation, then declines to undetectable levels within about a month in young children and within about three months in others.
How is this different from EBV VCA IgG?
VCA IgM is transient and fades within weeks to months, while VCA IgG persists for life once it appears. A clinician reads the two together to help place an infection in time.
What does a Epstein-Barr Virus Viral Capsid Antigen Antibody test cost without insurance?
$235. Celio Health's price is a flat cash price and insurance is never billed: the required physician's order is included.