RNP Antibody Test
The RNP antibody test looks for ribonucleoprotein (RNP) antibodies in a serum sample. Quest associates RNP antibodies with mixed connective tissue disease, which is the context in which this test's use is described.
About this test
RNP stands for ribonucleoprotein. This test looks for antibodies to RNP in the blood, using an immunoassay method on a 1 mL serum sample. A single antibody result is one data point, read by a clinician together with symptoms, history and any other autoantibody tests ordered at the same time.
Quest describes the RNP antibody test as associated with mixed connective tissue disease. That association is why the test may come up when a clinician is exploring symptoms that raise the possibility of a connective tissue condition, rather than as a stand-alone screening test for the general population.
Who might consider this test?
- People who consider this test are usually already working with a clinician on symptoms that suggest a connective tissue or autoimmune process.
Test details
| Collection | Quest patient service center |
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Quest resources
Additional details
What this test looks at
The test reports whether RNP antibodies are present in a serum sample, analyzed using immunoassay methodology. It does not look at any other antibody or marker; a broader autoimmune workup would combine it with separate tests ordered alongside it.
This test isn't part of the Celio Health store at the moment, so it can't be ordered or requested here. The test menu lists everything that can.
Laboratory results should always be interpreted by a licensed clinician who knows your health history. This page is information about a test, not medical advice.
Frequently asked questions
What does the RNP antibody test measure?
It measures the presence of RNP (ribonucleoprotein) antibodies in a serum sample, using immunoassay methodology.
How is the sample collected?
The test uses a 1 mL serum sample from a routine blood draw.
Do I need to prepare for an RNP antibody test?
No preparation instructions are listed for this test, though people follow any instructions their ordering clinician provides.
What condition is RNP antibody testing associated with?
Quest associates RNP antibodies with mixed connective tissue disease, which is the context in which this test's use is described.