Centromere B Antibody Test
The Centromere B Antibody test measures the level of centromere B antibody in a blood serum sample. Quest associates this antibody with CREST syndrome, a form of scleroderma.
About this test
Centromere B antibody is measured in serum using an immunoassay method. Quest describes it as associated with CREST syndrome, a form of scleroderma that involves calcinosis, Raynaud's phenomenon, esophageal immotility, sclerodactyly, and telangiectasia — the features the acronym CREST refers to.
Because the antibody is linked to this specific pattern of scleroderma features, a clinician reads a centromere B antibody result together with a person's symptoms and other findings rather than on its own.
Test details
| Collection | Quest patient service center |
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Quest resources
Additional details
What this test looks at
The test reports a single value: the level of centromere B antibody in a 1 mL serum sample. Quest describes this antibody as associated with CREST syndrome, a form of scleroderma.
This test isn't part of the Celio Health store at the moment, so it can't be ordered or requested here. The test menu lists everything that can.
Laboratory results should always be interpreted by a licensed clinician who knows your health history. This page is information about a test, not medical advice.
Frequently asked questions
What does the Centromere B Antibody test measure?
It measures the level of centromere B antibody in blood serum, using an immunoassay method. Quest associates this antibody with CREST syndrome, a form of scleroderma.
How is the sample collected?
The test uses a serum sample from a routine blood draw.
Do I need to prepare for this test?
No preparation instructions are listed for this test, though people follow any instructions their ordering clinician provides.
What is CREST syndrome?
Quest describes CREST syndrome as a form of scleroderma involving calcinosis, Raynaud's phenomenon, esophageal immotility, sclerodactyly, and telangiectasia, and lists centromere B antibody as associated with it.