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Lab test

IgE (Immunoglobulin E) Test

This test measures the level of immunoglobulin E (IgE) in a blood sample. IgE is an antibody type, and Quest describes this measurement as used in the evaluation of allergic disease.

Blood drawQuest patient service center

About this test

Immunoglobulin E, or IgE, is one of the classes of antibody the immune system produces. This test uses immunoassay methodology on a small serum sample to measure the overall level of IgE in the blood, and Quest lists it as a test used for evaluating allergic disease.

Quest also notes an important limit: a normal IgE level does not rule out the possible presence of an allergic disorder. Because of that, a clinician reads an IgE result together with symptoms, history and, often, other allergy-related testing rather than treating it as a stand-alone answer.

Test details

Quest code542
MethodologyImmunoassay
Sample type0.3 mL serum
CollectionQuest patient service center

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Quest resources

Additional details

What this test looks at

The test reports the overall level of IgE, one class of antibody, in a serum sample. It is a general measurement rather than a test for reaction to any specific substance.

Order online and a physician order is included — no doctor's visit and no insurance needed. Your sample is collected at a Quest Diagnostics patient service center.

Laboratory results should always be interpreted by a licensed clinician who knows your health history. This page is information about a test, not medical advice.

Frequently asked questions

What does this test measure?

It measures the overall level of immunoglobulin E (IgE) in a serum sample, using immunoassay methodology.

How is the sample collected?

The test uses a serum sample from a routine blood draw.

Do I need to prepare for this test?

No preparation instructions are listed for this test, though people follow any instructions their ordering clinician provides.

Does a normal IgE result rule out allergies?

No. Quest notes that a normal IgE level does not exclude the possible presence of an allergic disorder. A clinician reads it alongside symptoms and other findings.

Is this the same as allergen-specific testing?

No. This test measures the overall level of IgE rather than reaction to any particular substance. Allergen-specific testing is a separate kind of test.

How much is a IgE test?

$35, paid once at checkout. The price includes the physician's order this test requires and sample collection at a Quest patient service center.

Last updated 2026-09-18 · How we write about lab testing

Educational content

This page is for general educational purposes only. It is not medical advice, and it is not a substitute for consultation with a qualified healthcare professional. Laboratory results should always be interpreted by a licensed clinician who knows your health history. If you have questions about your health or your results, talk with your doctor. If you think you may be experiencing a medical emergency, call 911.