Estradiol, Ultrasensitive, LC/MS Test
This test measures estradiol in a serum sample using an ultrasensitive mass spectrometry method. Clinicians use it in evaluating ovarian function and, in men, in the evaluation of gynecomastia.
About this test
Estradiol is a hormone assessed with this test using chromatography/mass spectrometry, a highly sensitive method that can detect lower concentrations than more common estradiol assays. The sample is 0.
Estradiol assessment relates to ovarian function in situations such as menstrual disorders, precocious or delayed puberty, and assisted reproduction protocols, as well as to the evaluation of gynecomastia in men. Because the ultrasensitive method can pick up lower levels, it is generally used in situations where the standard estradiol test may not have enough sensitivity.
Who might consider this test?
- Often being evaluated for a menstrual disorder
- Precocious or delayed puberty
- As part of an assisted reproduction protocol
Test details
| Quest code | 30289 |
|---|---|
| Methodology | Chromatography/Mass Spectrometry |
| Sample type | 0.5 mL serum |
| Collection | Quest patient service center |
Related tests and panels
Measures Anti-Mullerian Hormone (AMH), a hormone associated with ovarian reserve.
Quest resources
Additional details
What this test looks at
The test reports a single value: the concentration of estradiol in serum, measured by chromatography/mass spectrometry rather than a standard immunoassay. This method is described as ultrasensitive, meaning it can detect lower concentrations of estradiol than more common testing approaches, which is why it is used in situations calling for that added sensitivity.
Order online and a physician order is included — no doctor's visit and no insurance needed. Your sample is collected at a Quest Diagnostics patient service center.
Laboratory results should always be interpreted by a licensed clinician who knows your health history. This page is information about a test, not medical advice.
Frequently asked questions
What does this test measure?
It measures the concentration of estradiol in a serum sample, using an ultrasensitive chromatography/mass spectrometry method.
How is the sample collected?
The test uses a 0.5 mL serum sample, collected in a red-top tube without gel, from a routine blood draw at a Quest Diagnostics patient service center.
Do I need to prepare for this test?
No preparation instructions are listed for this test, though people follow any instructions their ordering clinician provides.
Why might this test be ordered?
It may be used in assessment of ovarian function for menstrual disorders, precocious or delayed puberty, or assisted reproduction protocols, and in evaluation of gynecomastia in men.
Is this the same as a standard estradiol test?
Both measure estradiol, but this ultrasensitive method uses mass spectrometry and can detect lower concentrations than more common estradiol assays.
How much does the Estradiol Ultra-Sensitive test cost?
The cash price at Celio Health is $85. That covers the physician's order and sample collection at a Quest patient service center — no insurance is needed and there's no separate doctor's visit to pay for.