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Lab test

17-Hydroxyprogesterone Test

The 17-hydroxyprogesterone test measures the level of this hormone in a blood sample. Quest describes it as useful in evaluating congenital adrenal hyperplasia (CAH) and in monitoring related hormone therapy.

Blood drawQuest patient service center

About this test

17-hydroxyprogesterone is a hormone that is elevated in people with congenital adrenal hyperplasia, a group of inherited, autosomal recessive conditions marked by low cortisol and high ACTH. Quest lists this test under names such as 17-OHP and OH-Progesterone, alongside 17-Alpha-Hydroxprogesterone, and all refer to this same measurement.

The result is a single concentration of 17-hydroxyprogesterone in serum, measured using chromatography/mass spectrometry from a 0.5 mL blood sample collected in a red-top tube.

Who might consider this test?

  • Often working through an evaluation of congenital adrenal hyperplasia
  • Tracking cortisol replacement therapy over time
  • Looking into infertility or an adrenal or ovarian finding

Test details

Quest code17180
MethodologyChromatography/Mass Spectrometry
Sample type0.5 mL serum
CollectionQuest patient service center

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Quest resources

Additional details

What this test looks at

The test reports one value: the level of 17-hydroxyprogesterone in blood serum. Quest lists it under several names, including 17-OHP, OH-Progesterone and 17-Alpha-Hydroxprogesterone, which all describe the same hormone measurement.

Order online and a physician order is included — no doctor's visit and no insurance needed. Your sample is collected at a Quest Diagnostics patient service center.

Laboratory results should always be interpreted by a licensed clinician who knows your health history. This page is information about a test, not medical advice.

Frequently asked questions

What does the 17-hydroxyprogesterone test measure?

It measures the level of 17-hydroxyprogesterone in a serum sample, using chromatography/mass spectrometry. This hormone is elevated in people with congenital adrenal hyperplasia (CAH), a group of inherited conditions.

How is the 17-hydroxyprogesterone sample collected?

The test uses a 0.5 mL serum sample from a routine blood draw at a Quest Diagnostics patient service center.

Do I need to prepare for this test?

No preparation instructions are listed for this test, though people follow any instructions their ordering clinician provides.

Why might a clinician order this test?

Quest describes it as used in evaluating congenital adrenal hyperplasia, monitoring cortisol replacement therapy, and evaluating infertility or adrenal or ovarian neoplasms.

Is 17-OHP the same test?

Yes. 17-OHP, OH-Progesterone and 17-Alpha-Hydroxprogesterone are names Quest uses for this same 17-hydroxyprogesterone measurement.

How much does the 17-Hydroxyprogesterone test cost?

The cash price at Celio Health is $175. That covers the physician's order and sample collection at a Quest patient service center — no insurance is needed and there's no separate doctor's visit to pay for.

Last updated 2026-09-18 · How we write about lab testing

Educational content

This page is for general educational purposes only. It is not medical advice, and it is not a substitute for consultation with a qualified healthcare professional. Laboratory results should always be interpreted by a licensed clinician who knows your health history. If you have questions about your health or your results, talk with your doctor. If you think you may be experiencing a medical emergency, call 911.