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Lab test

Cardio IQ® Homocysteine Test

The Cardio IQ Homocysteine test measures the concentration of homocysteine, an amino acid, in a blood serum sample. Elevated homocysteine is considered an independent risk factor for cardiovascular disease, so clinicians may use this marker as part of assessing that risk.

Blood drawQuest patient service center

About this test

Homocysteine is an amino acid that circulates in the blood, and Quest describes elevated concentrations as an independent risk factor for cardiovascular disease. The test measures the level of homocysteine present in a serum sample, using an enzymatic method.

Because homocysteine is considered one risk factor among several, a clinician typically reads it alongside other cardiovascular markers and a person's broader history rather than treating it as a stand-alone answer.

Test details

Quest code91733
MethodologyEnzymatic
Sample type1 mL serum
CollectionQuest patient service center

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Quest resources

Additional details

What this test looks at

The test reports the concentration of homocysteine in a serum sample, measured with an enzymatic method. Quest lists this specific version under the Cardio IQ name.

How it's often used alongside other tests

Because Quest describes homocysteine as an independent risk factor, it is often ordered alongside standard lipid results and other cardiovascular markers rather than by itself, so a clinician can weigh it together with the rest of a person's risk picture.

Order online. No doctor's visit and no insurance needed. Your sample is collected at a Quest Diagnostics patient service center.

Laboratory results should always be interpreted by a licensed clinician who knows your health history. This page is information about a test, not medical advice.

Frequently asked questions

What does this test measure?

It measures the concentration of homocysteine, an amino acid, in a blood serum sample using an enzymatic method.

How is the sample collected?

Through a routine blood draw; the test uses a serum sample collected at a Quest Diagnostics patient service center.

Do I need to prepare for this test?

No preparation instructions are listed for this test. If a clinician has given you instructions, follow those.

Why is homocysteine linked to cardiovascular risk?

Quest describes elevated homocysteine concentrations as an independent risk factor for cardiovascular disease, which is why some clinicians include it as part of a broader cardiovascular risk assessment.

How much does the Cardio IQ Homocysteine test cost?

The test is $45, plus $25 for the doctor's order and Quest blood draw. Total: $70. The $25 fee is waived at $149+. See how ordering works and our blood test cost guide.

Last updated 2026-10-30 · How we write about lab testing

Educational content

This page is for general educational purposes only. It is not medical advice, and it is not a substitute for consultation with a qualified healthcare professional. Laboratory results should always be interpreted by a licensed clinician who knows your health history. If you have questions about your health or your results, talk with your doctor. If you think you may be experiencing a medical emergency, call 911.