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Lab test

Cardio IQ® APOE Genotype Test

The Cardio IQ APOE Genotype test determines the genetic subtype, or genotype, of the APOE gene from a blood sample. Quest describes this genotype information as an aid in assessing risk related to coronary heart disease and hyperlipoproteinemia.

Blood drawQuest patient service center

About this test

APOE is a gene, and this test determines which subtype, or genotype, a person carries. Quest describes the result as an aid to assessing risk associated with coronary heart disease and hyperlipoproteinemia, a condition involving elevated lipoprotein levels in the blood.

Because this is a genetic test, the result reflects an inherited genotype rather than a value that changes over time the way many blood chemistry markers do. Quest's report format for this test includes interpretive guidance and commentary alongside the genotype result, which is part of how the result is meant to be read by the ordering clinician.

Test details

Quest code90649
MethodologyReal-Time Polymerase Chain Reaction
Sample type4 mL whole blood
CollectionQuest patient service center

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Quest resources

Additional details

What this test looks at

The test reports the APOE genotype determined from a whole blood sample, along with interpretive guidance and commentary that Quest includes as part of the result. Quest lists this test under several names, including Apolipoprotein E Genotype and APOE Genotype, which all refer to the same test.

Order online and a physician order is included — no doctor's visit and no insurance needed. Your sample is collected at a Quest Diagnostics patient service center.

Laboratory results should always be interpreted by a licensed clinician who knows your health history. This page is information about a test, not medical advice.

Frequently asked questions

What does this test measure?

It determines the genotype, or subtype, of the APOE gene from a whole blood sample, analyzed using real-time PCR.

How is the sample collected?

The test uses a whole blood sample collected at a Quest Diagnostics patient service center.

Do I need to prepare for this test?

No preparation instructions are listed for this test, though people follow any instructions their ordering clinician provides.

Is this the same as an Apolipoprotein E Genotype test?

Yes. Quest lists this test under several names, including CardioIQ, Apolipoprotein E Genotype and APOE Genotype, and they refer to the same genetic test.

How much does the Cardio IQ ApoE Genotype test cost?

The cash price at Celio Health is $295. That covers the physician's order and sample collection at a Quest patient service center — no insurance is needed and there's no separate doctor's visit to pay for.

Last updated 2026-09-18 · How we write about lab testing

Educational content

This page is for general educational purposes only. It is not medical advice, and it is not a substitute for consultation with a qualified healthcare professional. Laboratory results should always be interpreted by a licensed clinician who knows your health history. If you have questions about your health or your results, talk with your doctor. If you think you may be experiencing a medical emergency, call 911.