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Lab test

Apolipoprotein Evaluation Test

The apolipoprotein evaluation measures two proteins, apolipoprotein A1 and apolipoprotein B-100, along with the ratio between them, in a blood sample. Both are associated with cardiovascular disease risk.

Blood drawQuest patient service center

About this test

Apolipoprotein A1 is the primary protein associated with HDL cholesterol, and apolipoprotein B-100 is the primary protein associated with LDL cholesterol and other lipid particles. Increased apolipoprotein A1 is associated with reduced cardiovascular disease risk, while increased apolipoprotein B-100 is associated with increased risk, and the ratio between the two also correlates with cardiovascular disease risk.

The evaluation uses a 1 mL serum sample, analyzed with an immunoturbidimetric method. It reports concentrations of both apolipoproteins plus their calculated ratio, which a clinician reads alongside other lipid results rather than on its own.

Test details

Quest code7018
MethodologyImmunoturbidimetric
Sample type1 mL serum
CollectionQuest patient service center

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Additional details

What this test looks at

The evaluation reports three values: apolipoprotein A1, apolipoprotein B-100, and the ratio between them. Apolipoprotein A1 relates to HDL cholesterol and apolipoprotein B-100 relates to LDL cholesterol and other lipid particles.

How it's often used alongside other tests

Because both proteins and their ratio are described as correlating with cardiovascular disease risk, this evaluation is typically read alongside a broader lipid picture and personal history rather than by itself. A clinician weighs the combination rather than any single number.

Order online and a physician order is included — no doctor's visit and no insurance needed. Your sample is collected at a Quest Diagnostics patient service center.

Laboratory results should always be interpreted by a licensed clinician who knows your health history. This page is information about a test, not medical advice.

Frequently asked questions

What does the apolipoprotein evaluation measure?

It measures the concentrations of apolipoprotein A1 and apolipoprotein B-100 in a serum sample, along with the ratio between them, using an immunoturbidimetric method.

How is the sample collected?

The test uses a 1 mL serum sample collected through a routine blood draw.

Do I need to prepare for this test?

No preparation instructions are listed for this test, though people follow any instructions their ordering clinician provides.

Why might this evaluation be ordered?

Apolipoprotein A1 is associated with reduced cardiovascular disease risk, apolipoprotein B-100 with increased risk, and the ratio between them also correlates with cardiovascular disease risk, which is why the combination may be included in a risk evaluation.

How much is a Cardio Apolipoprotein Evaluation test?

$99, paid once at checkout. The price includes the physician's order this test requires and sample collection at a Quest patient service center.

Last updated 2026-09-18 · How we write about lab testing

Educational content

This page is for general educational purposes only. It is not medical advice, and it is not a substitute for consultation with a qualified healthcare professional. Laboratory results should always be interpreted by a licensed clinician who knows your health history. If you have questions about your health or your results, talk with your doctor. If you think you may be experiencing a medical emergency, call 911.