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Lab test

Hepatitis A IgM Antibody Test

A hepatitis A IgM antibody test looks for IgM antibodies to the hepatitis A virus, a class of antibody the immune system typically produces early in the body's response. Clinicians use it as part of the evaluation of a recent hepatitis A picture, always interpreted in context.

Blood drawQuest patient service center

About this test

Antibodies are proteins the immune system makes when it encounters something it recognizes as foreign, such as a virus. IgM is one class of antibody, and the body generally produces it comparatively early in a response before shifting toward other classes over time.

The test is done with a simple blood draw at a patient service center. A phlebotomist collects a sample from a vein, usually in the arm, and sends it to the laboratory.

Who might consider this test?

  • Encounter this test when a clinician is evaluating signs that can be linked to the liver — such as yellowing of the skin or eyes
  • Abdominal discomfort — and wants to consider hepatitis A as part of the picture
  • It may also come up after a possible exposure or during a broader evaluation of liver-related symptoms.

Test details

Quest code512
MethodologyImmunoassay
Sample type1 mL serum
CollectionQuest patient service center

Reference range

Non-Reactive

Reference ranges are general guidance. The range printed on your own laboratory report is the one that applies to your result.

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Additional details

What this test looks at

The test looks for IgM-class antibodies against the hepatitis A virus in the blood. Because the immune system tends to raise IgM comparatively early in its response, this marker is used to help a clinician evaluate a recent time frame rather than a long-standing history of exposure. It is one input a clinician weighs, not a verdict on its own.

It helps to distinguish antibody classes. IgM and IgG serve different roles in the immune response and appear on different timelines, which is why a clinician may consider more than one antibody test to build a clearer sense of where a person is in that timeline.

How it's often used alongside other tests

The hepatitis A IgM test is frequently read within a broader evaluation. It may sit alongside liver enzymes such as ALT and AST, bilirubin, and other hepatitis markers, so a clinician can view the immune signal and the liver picture together. Depending on the situation, IgG antibody testing may also be considered to help place a person along the timeline. Read together, these results give a clinician a fuller view than the IgM marker alone.

Order online and a physician order is included — no doctor's visit and no insurance needed. Your sample is collected at a Quest Diagnostics patient service center.

Laboratory results should always be interpreted by a licensed clinician who knows your health history. This page is information about a test, not medical advice.

Frequently asked questions

What does the hepatitis A IgM antibody test look for?

It looks for IgM-class antibodies to the hepatitis A virus. IgM is a class the immune system generally produces early in its response, so the test is oriented toward a recent time frame.

How is IgM different from IgG?

IgM and IgG are different antibody classes that appear on different timelines. IgM tends to rise earlier, while IgG appears later, so a clinician may consider both to place a person along the timeline.

Why might someone consider this test?

It is often used when a clinician is evaluating liver-related symptoms or a possible exposure and wants to consider hepatitis A as part of the picture.

How is the sample collected?

Through a routine blood draw at a patient service center. A phlebotomist takes a small sample from a vein in the arm and sends it to the laboratory.

Can this test diagnose hepatitis A on its own?

No. A single marker does not establish a diagnosis by itself. A clinician interprets the antibody result together with symptoms, timing, exposure history, and other markers.

Can I get the Hepatitis A IgM Antibody test without a doctor's visit or insurance?

Yes. The $79 cash price includes an independent physician's order, so no referral is needed, and insurance is never involved.

Last updated 2026-09-18 · How we write about lab testing

Educational content

This page is for general educational purposes only. It is not medical advice, and it is not a substitute for consultation with a qualified healthcare professional. Laboratory results should always be interpreted by a licensed clinician who knows your health history. If you have questions about your health or your results, talk with your doctor. If you think you may be experiencing a medical emergency, call 911.