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Lab test

Lithium Test

The lithium test measures the concentration of lithium in a blood sample. Lithium is a medication used in the care of manic-depressive disorders, and Quest describes this test as a way to help track levels of the medication in the blood.

Blood drawSpecial preparation requiredQuest patient service center

About this test

Lithium is a medication used in the care of manic-depressive disorders and the manic phase of affective disorders. Quest describes lithium as having a relatively small therapeutic window, which is why monitoring blood levels is useful for helping optimize dosing.

The test can be run using several laboratory methods, including immunoassay, inductively coupled plasma/mass spectrometry, spectrometry or spectrophotometry, and Quest notes that the sample is generally collected just before the next dose so the result reflects a consistent point in the dosing cycle.

Test details

Quest code613
MethodologyImmunoassay • Inductively Coupled Plasma/Mass Spectrometry • Spectrometry • Spectrophotometry
Sample type2 mL serum
Patient preparationCollect just before your next dose.
CollectionQuest patient service center

Reference range

0.6-1.2 mmol/L

Reference ranges are general guidance. The range printed on your own laboratory report is the one that applies to your result.

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Quest resources

Additional details

What this test looks at

The test reports one value: the concentration of lithium in a serum sample, used to track levels of the medication in the blood over the course of treatment.

Order online and a physician order is included — no doctor's visit and no insurance needed. Your sample is collected at a Quest Diagnostics patient service center.

Laboratory results should always be interpreted by a licensed clinician who knows your health history. This page is information about a test, not medical advice.

Frequently asked questions

What does the lithium test measure?

It measures the concentration of lithium in a blood serum sample, used to track levels of the medication.

How is the lithium sample collected?

The test uses a serum sample from a routine blood draw.

Do I need to prepare for a lithium test?

Yes. Quest lists a preparation instruction for this test tied to the timing of the blood draw relative to a dose, which appears with the test details; people follow the instructions their ordering clinician provides.

Why is lithium monitored with blood tests?

Quest describes lithium as having a relatively small therapeutic window, so monitoring blood levels is useful for helping optimize dosing and avoid levels that are too high or too low.

How much is a Lithium test?

$75, paid once at checkout. The price includes the physician's order this test requires and sample collection at a Quest patient service center.

Do I need to prepare for this test?

Collect just before your next dose. This is the preparation Quest publishes for this test; if your clinician gives you different instructions, follow theirs.

Last updated 2026-09-18 · How we write about lab testing

Educational content

This page is for general educational purposes only. It is not medical advice, and it is not a substitute for consultation with a qualified healthcare professional. Laboratory results should always be interpreted by a licensed clinician who knows your health history. If you have questions about your health or your results, talk with your doctor. If you think you may be experiencing a medical emergency, call 911.