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Lab test

Bismuth, Random Urine with Creatinine Test

This test measures bismuth in a random urine sample, reported together with creatinine to account for how concentrated the urine is. Quest describes it as used in evaluating bismuth exposure associated with bismuth-containing medications.

Quest patient service center

About this test

Bismuth is a metal found in some over-the-counter medications, including Pepto-Bismol. Quest describes this test as measuring the amount of bismuth present in a random urine sample, reported together with creatinine so the result reflects concentration rather than however dilute or concentrated a single urine sample happens to be.

Quest notes that excessive use of bismuth-containing medications may cause renal damage and other adverse effects, and that this test may be used in evaluating exposure associated with that use. A single urine result is read alongside a person's history of medication use and any other findings a clinician has.

Test details

CollectionQuest patient service center

Quest resources

Additional details

What this test looks at

The test reports two values from the same random urine sample: bismuth and creatinine. Quest's preparation notes ask that mineral supplements and bismuth preparations such as Pepto-Bismol be avoided for at least a week before the sample is collected, since ongoing use could affect the result.

This test isn't part of the Celio Health store at the moment, so it can't be ordered or requested here. The test menu lists everything that can.

Laboratory results should always be interpreted by a licensed clinician who knows your health history. This page is information about a test, not medical advice.

Frequently asked questions

What does this test measure?

It measures the amount of bismuth in a random urine sample, reported together with creatinine, using Inductively Coupled Plasma/Mass Spectrometry.

How is the sample collected?

The test uses a 7 mL random urine sample collected in an acid-washed or metal-free container.

Do I need to prepare for this test?

Quest asks that mineral supplements and bismuth preparations such as Pepto-Bismol be avoided for at least one week before the sample is collected.

Why is bismuth measured in urine?

Quest describes this test as used in evaluating bismuth exposure related to bismuth-containing medications, since excessive use of those products has been associated with renal and other effects. A clinician reads the result together with a person's medication history.

Last updated 2026-09-18 · How we write about lab testing

Educational content

This page is for general educational purposes only. It is not medical advice, and it is not a substitute for consultation with a qualified healthcare professional. Laboratory results should always be interpreted by a licensed clinician who knows your health history. If you have questions about your health or your results, talk with your doctor. If you think you may be experiencing a medical emergency, call 911.