Factor V (Leiden) Mutation Analysis
The Factor V (Leiden) Mutation Analysis test analyzes DNA from a whole blood sample to look for the factor V Leiden variant. Quest describes this variant as the most common inherited cause of increased blood clotting risk.
About this test
This test uses polymerase chain reaction and detection methods to examine DNA from a whole blood sample for the factor V Leiden variant in the FV gene. Quest describes this variant as associated with resistance to the normal breakdown of a clotting protein, which is linked to an increased risk of venous thromboembolism.
Who might consider this test?
- A genetic finding like this one is typically one piece of a broader clotting-risk workup rather than the only input a clinician relies on.
Test details
| Collection | Quest patient service center |
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Quest resources
Additional details
This test isn't part of the Celio Health store at the moment, so it can't be ordered or requested here. The test menu lists everything that can.
Laboratory results should always be interpreted by a licensed clinician who knows your health history. This page is information about a test, not medical advice.
Frequently asked questions
What does the Factor V (Leiden) Mutation Analysis measure?
It analyzes DNA from a whole blood sample to detect the factor V Leiden variant in the FV gene, a genetic change Quest associates with resistance to normal clotting-protein breakdown and an increased risk of venous thromboembolism.
How is the sample collected?
The test uses a whole blood sample from a routine blood draw, analyzed by polymerase chain reaction and detection methods.
Do I need to prepare for this test?
No preparation instructions are listed for this test, though people follow any instructions their ordering clinician provides.
What does the test report?
It reports whether the factor V Leiden variant is present, along with an interpretation of that finding, so a clinician can read the result in context.