Copper, RBC Test
The Copper, RBC test measures the concentration of copper within red blood cells. Copper is an essential element that serves as a cofactor for numerous enzymes in the body.
About this test
This test reports the amount of copper found inside red blood cells, distinct from copper measured in whole blood or serum. Quest analyzes a red blood cell sample, collected in an EDTA trace metal-free tube, using inductively coupled plasma/mass spectrometry (ICP/MS).
Quest describes copper metabolism as disturbed in conditions such as Wilson's disease, Menkes disease, primary biliary cirrhosis and Indian childhood cirrhosis. Concentrations are described as increasing in acute phase reactions and decreasing with nephrosis, malabsorption or malnutrition.
Who might consider this test?
- Often being evaluated for a condition tied to copper metabolism
- Such as Wilson's disease or Menkes disease
- Are having copper levels monitored as part of nutritional supplementation
Test details
| Quest code | 3481 |
|---|---|
| Methodology | Inductively Coupled Plasma/Mass Spectrometry |
| Sample type | 0.5 mL red blood cells |
| Collection | Quest patient service center |
Reference range
0.53-0.91 mg/L
Reference ranges are general guidance. The range printed on your own laboratory report is the one that applies to your result.
Related tests and panels
Quest resources
Additional details
What this test looks at
The test reports the concentration of copper specifically within red blood cells, using inductively coupled plasma/mass spectrometry on a 0.5 mL sample. This is different from copper measured in whole blood, which is a separate Quest product.
How it's often used alongside other tests
Quest notes that results from this test are often interpreted together with ceruloplasmin. Reading the two together gives a clinician more context on copper status than either result alone.
Order online and a physician order is included — no doctor's visit and no insurance needed. Your sample is collected at a Quest Diagnostics patient service center.
Laboratory results should always be interpreted by a licensed clinician who knows your health history. This page is information about a test, not medical advice.
Frequently asked questions
What does the Copper, RBC test measure?
It measures the concentration of copper within red blood cells, using inductively coupled plasma/mass spectrometry.
How is the sample collected?
The test uses a 0.5 mL red blood cell sample, collected in an EDTA trace metal-free tube, during a routine blood draw at a Quest Diagnostics patient service center.
Do I need to prepare for this test?
No preparation instructions are listed for this test, though people follow any instructions their ordering clinician provides.
Why might this test be ordered?
Quest describes copper metabolism as disturbed in conditions such as Wilson's disease, Menkes disease, primary biliary cirrhosis and Indian childhood cirrhosis, and notes the test is also used to monitor nutritional supplementation, particularly in preterm newborns.
Is Copper, RBC the same as the whole blood copper test?
No. This test measures copper specifically within red blood cells. Copper, Blood is a separate product that measures copper in whole blood.
What does a Copper RBC test cost without insurance?
$199. Celio Health's price is a flat cash price and insurance is never billed: the required physician's order is included.