Beta-2-Microglobulin, Serum Test
This test measures beta-2-microglobulin in a blood sample. Because this protein is normally filtered and reabsorbed by the kidney, its serum level reflects glomerular filtration function.
About this test
Beta-2-microglobulin is measured in serum using an immunoturbidometric method. Quest describes serum levels as an index of glomerular filtration rate: the level declines after a successful kidney transplant and rises as an early sign of rejection.
People considering this test are typically being monitored for kidney transplant function or evaluated for a renal, lymphoproliferative, or related condition by their clinician, since Quest describes the marker as relevant across each of those areas rather than as a single-purpose screen.
Test details
| Collection | Quest patient service center |
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Quest resources
Additional details
What this test looks at
The result is a single value: the concentration of beta-2-microglobulin in a serum sample. Quest lists the methodology used to produce that value as immunoturbidometric.
This test isn't part of the Celio Health store at the moment, so it can't be ordered or requested here. The test menu lists everything that can.
Laboratory results should always be interpreted by a licensed clinician who knows your health history. This page is information about a test, not medical advice.
Frequently asked questions
What does this test measure?
It measures the amount of beta-2-microglobulin in a serum sample using an immunoturbidometric method.
How is the sample collected?
The test uses a 1 mL serum sample from a routine blood draw.
Do I need to prepare for this test?
No preparation instructions are listed for this test, though people follow any instructions their ordering clinician provides.
Why is beta-2-microglobulin linked to kidney function?
Quest describes it as normally filtered and reabsorbed by the kidney, so its serum level is used as an index of glomerular filtration rate, declining after a successful transplant and rising as an early sign of rejection.
Is beta-2-microglobulin only used for kidney monitoring?
No. Quest notes it may also be used in evaluating lymphoproliferative disorders, neoplasms, inflammatory disease, and autoimmune conditions such as lupus and Sjogren's disease.